True or False: Cancer cells become spherical when crowded but can still divide.

Cancer cells exhibit unique properties that differentiate them from normal cells, particularly in how they respond to crowding. Under conditions where they become densely packed, cancer cells can lose their typical flat shape and adopt a more spherical form. This morphological change is a consequence of the abnormal signaling pathways and growth factor responses that characterize cancer cells.

Even when these cells are crowded and have transformed into a spherical shape, they maintain their ability to divide. This is a key characteristic of cancer cells, as they often evade the normal regulatory mechanisms that would stop proliferation under such conditions. Normal cells typically experience growth arrest when crowded, a phenomenon known as contact inhibition, but cancer cells can bypass this restriction, resulting in unchecked proliferation regardless of their shape or density.

Thus, affirming the statement reflects an understanding of cancer cell behavior, particularly their ability to grow and divide even when physical constraints, such as crowding, trigger significant changes in their morphology.